Offline availability of precomputed scores

Hi @matthdsm,

Welcome to the forum!

Yes, we provide datasets that you can download for offline computation here (https://alphagenome.google/downloads). The AVI scores are availble under a permissive license, with other datasets available for non-commercial use.

ENSEMBL have already integrated the AVI scores into VEP, as well as UCSC into their genome browser, so hopefully these will allow easy annotation with any existing pipelines you may have.

Tom