Hi,
Are there any plans to publish a dataset containing precomputed scores for high throughput (offline) variant annotation through the likes of Ensembl VEP etc. ?
This would be a great feature to have and could direct people to the API for more thorough queries.
Thanks!
Hi @matthdsm,
Welcome to the forum!
Yes, we provide datasets that you can download for offline computation here (https://alphagenome.google/downloads). The AVI scores are availble under a permissive license, with other datasets available for non-commercial use.
ENSEMBL have already integrated the AVI scores into VEP, as well as UCSC into their genome browser, so hopefully these will allow easy annotation with any existing pipelines you may have.
Tom
Hi @tward ,
Thanks for the quick reply! I can’t believe I missed VEP and UCSC 