Protobuf gencode version mismatch warning during AlphaGenome initialization

Help & Support
1

Hi,

While initializing the AlphaGenome model, I’m seeing the following warnings:

UserWarning: Protobuf gencode version 5.27.2 is exactly one major version older than the runtime version 6.31.1 at alphagenome/protos/dna_model.proto. Please update the gencode to avoid compatibility violations in the next runtime release.
warnings.warn(
/gpfs/data/user/shweta_lab/data/SKAN/analyses/alphagenome-env/lib/python3.11/site-packages/google/protobuf/runtime_version.py:98: UserWarning: Protobuf gencode version 5.27.2 is exactly one major version older than the runtime version 6.31.1 at alphagenome/protos/tensor.proto. Please update the gencode to avoid compatibility violations in the next runtime release.
warnings.warn(

This appears right before:

Initializing the AlphaGenome model...

I wanted to check: Is this warning expected and safe to ignore for now? Or should I manually update the gencode version to match the runtime version (6.31.1)? If yes, could you please suggest the recommended way to update gencode in AlphaGenome?

Thanks!

2

Thanks for reaching out. Yes, the warning regarding the Protobuf gencode version mismatch is expected and can be safely ignored.