# Reference genome coordinate conversion

**URL:** <https://www.alphagenomecommunity.com/t/reference-genome-coordinate-conversion/952>\
**Category:** Help & Support\
**Created:** [July 29, 2026, 6:09pm UTC](https://www.alphagenomecommunity.com/t/reference-genome-coordinate-conversion/952 "2026-07-29T18:09:44Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![zhen\_zhao](https://yyz2.discourse-cdn.com/watermelon/user_avatar/www.alphagenomecommunity.com/zhen_zhao/32/1230_2.png) [@zhen\_zhao](https://www.alphagenomecommunity.com/u/zhen_zhao)\
**Post date:** [July 29, 2026, 6:09pm UTC](https://www.alphagenomecommunity.com/t/reference-genome-coordinate-conversion/952/1 "2026-07-29T18:09:44Z")

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The article uses the hg38 reference genome for its analyses. **My question is: can I perform the conversion using reference genomes from other human populations or specific ethnic groups instead?**

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**Author:** ![Tumi\_Makgatho](https://yyz2.discourse-cdn.com/watermelon/user_avatar/www.alphagenomecommunity.com/tumi_makgatho/32/703_2.png) [@Tumi\_Makgatho](https://www.alphagenomecommunity.com/u/Tumi_Makgatho)\
**Post date:** [August 7, 2026, 2:06pm UTC](https://www.alphagenomecommunity.com/t/reference-genome-coordinate-conversion/952/2 "2026-08-07T14:06:41Z")

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Hi There!

Thanks for reaching out.

Yes you can into a genomic sequence and use predict\_sequence. The benefit of predict\_interval is that it uses the gene annotations of the reference, which is important for some of the scoring methodologies employed by score\_variant. The gene annotation are also really helpful for plotting purposes. I recommend you use a coordinate conversion tool like liftover to move from (eg) hg19 to hg38.

Kind regards,  
Tumi